NEWS: March 14th, 2013 - YADAMP is updated to 2525 sequences
NEWS: October 5th, 2012 - YADAMP is updated to 2472 sequences
NEWS: May 12th, 2012 - YADAMP now permits taxonomic queries
YADAMP is born to facilitate the access to important information on AMPs. Particular attention is given to short alpha helix peptides interacting with cell membranes. At the moment, the database contains 2525 manually annotated sequences. YADAMP permits a quick and easy search of peptides on the base of their activity (expressed as MIC against several bacterial strains) and of their structure.
The philosophy behind YADAMP is to permit extensive QSAR analysis and the creation of activity model against a particular bacterial target. You can search through the database selecting as many fields as you like. The combination is equivalent to the logic AND. Some of the fields contains calculated values (i.e. helicity or hydrophobic moments). Check the page Theory for information about the methods exploited.
If you find YADAMP useful for your research, please cite us.
YADAMP: yet another database of antimicrobial peptides; Stefano Piotto, Lucia Sessa, Simona Concilio, Pio Iannelli, International Journal of Antimicrobial Agents, 39, 4, (2012), 346–351 pdf
Disclaimer: The authors do not assume any responsibility for losses of any kind incurred by use of this database.
Acknowledgements : YADAMP is born from the work on antimicrobial peptides of Prof. Stefano Piotto, but it would not exist in its present form without the support or the collaboration of: Prof. Giuseppe Cattaneo, Dr. Aniello Castiglione, Luigi Di Biasi (Department of Informatics, Univ. Salerno, Italy), Prof. Simona Concilio, Dr. Erminia Bianchino (BioGem), Lucia Sessa, Federica Campana, Eda Graceni, Giacomo Di Lorenzo, Carla Monaco (Department of Pharmaceutical and Biomedical Sciences, Univ. Salerno, Italy). YADAMP is a product of the Lab of Material Sciences @Univ. Salerno